Manchester United suffered a heavy 4-1 defeat away to tournament debutants Como in the Champions League, leaving manager Michael Carrick without a win in seven games.
Declan Rice scored an 82nd-minute equaliser for Arsenal to secure a 2-2 draw against Bayern Munich after Harry Kane converted a second-half penalty for his 10th goal this season.
Real Madrid defeated RB Leipzig 4-1 with goals from Bernardo Silva, Arda Guler, Kylian Mbappe, and Yan Diomande to maintain a perfect record in the competition.