Pomegranate Compound Shows Potential for Treating Heart Failure

A study published in Science Advances indicates that urolithin A, a compound derived from pomegranates and walnuts, may improve heart function in cases of heart failure with preserved ejection fraction.

Researchers observed that the compound improved heart function by up to 80% in animal models and enhanced tissue relaxation in engineered human heart cells by targeting the PKG1alpha protein.

While the findings offer a potential new strategy for treating the condition that affects approximately 32 million of the 64 million global heart failure patients, clinical trials are required to confirm human efficacy.