Health & Environment
BCG Vaccine Shows Potential for Alzheimer’s Intervention
The Hindu1h
THE BRIEF
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A study in Communications Medicine suggests the BCG tuberculosis vaccine may retrain innate immune cells in the brain to help clear amyloid-beta plaques associated with Alzheimer’s.
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Researchers at Massachusetts General Hospital observed that in participants without established Alzheimer’s, the vaccine appeared to facilitate the movement of amyloid from the brain into the blood.
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The study involved 23 older adults who received two BCG doses, though researchers noted the treatment showed limited efficacy in patients with already established dementia.