
Researchers at Texas A&M are using a $1.65 million NIH grant to investigate how paternal sperm epigenetics contribute to early pregnancy loss in cattle.
The study focuses on histones and non-genetic DNA changes, aiming to identify biomarkers in high and low-fertility bulls that predict abnormal embryo development.
By using cattle as a model for human fertility, the team hopes to develop future treatments to improve live birth rates, as over 50% of human conceptions fail to result in birth.