Research from Edith Cowan University indicates that the AQP4 gene, which regulates brain waste removal, influences how poor sleep affects Alzheimer's-related brain changes.
Study participants with specific AQP4 variants showed faster grey matter loss when reporting shorter sleep durations, impacting memory and decision-making functions.
The findings, published in the journal 'Alzheimer’s & Dementia', suggest that personalized prevention strategies based on genetics and sleep habits are necessary.