
A study published in Nature Aging analyzed 25,000 tissue samples from 970 donors and found that human bodies undergo two distinct bursts of accelerated structural aging.
Researchers identified these bursts typically occurring in the 30s and 50s, with the ovaries acting as a potential pacemaker for whole-body aging in many tissues.
The structural changes, which include increased inflammation and reduced energy production, were observed across 40 tissue types, including the esophagus, stomach, and colon.