
Archibald V. Hill and Otto Meyerhof shared the 1922 Nobel Prize in Physiology or Medicine for their foundational discoveries regarding energy generation and recovery in muscles.
Hill was recognized for discovering heat production during muscle contraction, demonstrating that recovery heat continues in phases dependent on oxygen.
Meyerhof investigated chemical changes, showing that carbohydrate is converted into lactic acid during muscle activity and partially oxidized or reconverted during recovery.