
A NIMHANS study of 89 laboratory-confirmed rabies deaths found that true vaccine failure is rare, with most cases linked to deviations in post-exposure prophylaxis (PEP).
Researchers identified critical lapses such as inadequate wound washing, incorrect vaccine injection sites, and failure to properly administer rabies immunoglobulin for Category III bites.
India records approximately 9.1 million animal bites annually, resulting in an estimated 5,726 human rabies deaths, according to 2024 ICMR-NIE data.